Stable establishment of wMel Wolbachia in Aedes aegypti populations in Yogyakarta, Indonesia

Autor: Dwi Satria Wardana, Iva Fitriana, Bekti Andari, Hilmi Ardiansyah, Munasdi Victorius, Inggrid Ernesia, Petrina H. Johnson, Scott Leslie O'Neill, Nida Budiwati, Edwin Widyanto Daniwijaya, Dedik H Yusdiana, Adi Utarini, Peter A. Ryan, Andrew P. Turley, Warsito Tantowijoyo, Edwige Rancès, Indah Nurhayati, Ary A. Hoffmann, Endah Supriyati, Eggi Arguni, Riris Andono Ahmad, Cameron P. Simmons
Jazyk: angličtina
Rok vydání: 2020
Předmět:
0301 basic medicine
Male
Viral Diseases
Life Cycles
RC955-962
Disease Vectors
Mosquitoes
Zika virus
law.invention
Geographical Locations
0302 clinical medicine
Larvae
law
Aedes
Arctic medicine. Tropical medicine
Medicine and Health Sciences
reproductive and urinary physiology
biology
Eukaryota
Insects
Transmission (mechanics)
Infectious Diseases
Biological Control Agents
Arboviral Infections
Viruses
Wolbachia
Female
Public aspects of medicine
RA1-1270
Research Article
Asia
Arthropoda
030231 tropical medicine
Oceania
Zoology
Aedes aegypti
Mosquito Vectors
Aedes Aegypti
Arbovirus
03 medical and health sciences
parasitic diseases
medicine
Disease Transmission
Infectious
Animals
Bacteria
fungi
Public Health
Environmental and Occupational Health
Australia
Organisms
Biology and Life Sciences
biochemical phenomena
metabolism
and nutrition
biology.organism_classification
medicine.disease
Invertebrates
Insect Vectors
Species Interactions
030104 developmental biology
Parasitology
Indonesia
People and Places
Biological dispersal
bacteria
Arboviruses
Developmental Biology
Zdroj: PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 14, Iss 4, p e0008157 (2020)
DOI: 10.1371/journal.pntd.0008157
Popis: The successful establishment of the wMel strain of Wolbachia for the control of arbovirus transmission by Aedes aegypti has been proposed and is being implemented in a number of countries. Here we describe the successful establishment of the wMel strain of Wolbachia in four sites in Yogyakarta, Indonesia. We demonstrate that Wolbachia can be successfully introgressed after transient releases of wMel-infected eggs or adult mosquitoes. We demonstrate that the approach is acceptable to communities and that Wolbachia maintains itself in the mosquito population once deployed. Finally, our data show that spreading rates of Wolbachia in the Indonesian setting are slow which may reflect more limited dispersal of Aedes aegypti than seen in other sites such as Cairns, Australia.
Author summary We show that the wMel strain of Wolbachia can be deployed successfully into mosquito populations in an area of intense dengue transmission in Yogyakarta, Indonesia. Deployment was achieved through either the release of eggs or adult mosquitoes with full community support. This represents the successful first step toward a large trial to evaluate the use of Wolbachia in Indonesia to disrupt transmission of arboviruses such as dengue, Zika and chikungunya.
Databáze: OpenAIRE
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