Microbiological and Biochemical Effectiveness of an Antiseptic Gel on the Bacterial Contamination of the Inner Space of Dental Implants: A 3-Month Human Longitudinal Study
| Autor: | Simonetta D'Ercole, Giuseppe Spoto, Stefano Tetè, Michele Paolantonio, Beatrice Femminella, G Catamo, Domenico Tripodi, Gilberto Sammartino |
|---|---|
| Přispěvatelé: | D'Ercole, S., Tetè, S., Catamo, G., Sammartino, Gilberto, Femminella, B., Tripodi, D., Spoto, G., Paolantonio, M. |
| Rok vydání: | 2009 |
| Předmět: |
Adult
Male Peri-implantitis medicine.medical_specialty Prosthesis-Related Infections Time Factors medicine.drug_class medicine.medical_treatment Immunology Colony Count Microbial Dentistry Connective tissue Dental Abutments Ribotyping contamination Antiseptic Humans Immunology and Allergy Medicine Aspartate Aminotransferases Longitudinal Studies Prosthesis-Related Infection Dental Implants Pharmacology Crowns business.industry Chlorhexidine Middle Aged Surgery Radiography antiseptic gel Treatment Outcome medicine.anatomical_structure Anti-Infective Agents Local Female Implant Dentures business Gels Biomarkers medicine.drug |
| Zdroj: | International Journal of Immunopathology and Pharmacology. 22:1019-1026 |
| ISSN: | 2058-7384 |
| DOI: | 10.1177/039463200902200417 |
| Popis: | Microbial penetration inside the implant's internal cavity produces a bacterial reservoir that is associated with an area of inflamed connective tissue facing the fixture-abutment junction. The aim of this clinical trial is to evaluate the effectiveness of a 1% chlorhexidine gel on the internal bacterial contamination of implants with screw-retained abutments and on the level of AST secreted in peri-implant crevicular fluid. Twenty-five patients (aged 29 to 58 years) each received one implant. Three months after the end of the restorative treatment, and immediately after a clinical and radiographic examination and the abutment removal, microbiological samples were obtained from the internal part of each fixture and biochemical samples were collected by peri-implant sulci. The patients were then divided into two groups: the control (CG; n=10) and test (TG; n=15) groups. The CG had the abutment screwed into place and the crown cemented without any further intervention. In contrast, before the abutment placement and screw tightening, the TG had the internal part of the fixture filled with a 1% chlorhexidine gel. Three months later, the same clinical, microbiological and biochemical procedures were repeated in both groups. Total bacterial count, specific pathogens and AST activity were detected. The clinical parameters remained stable throughout the study. From baseline to the 3-month examination, the total bacterial counts underwent a significant reduction only in the TG. In contrast, the AST activity showed a significant increase in the CG. The administration of a 1% chlorhexidine gel appears to be an effective method for the reduction of bacterial colonization of the implant cavity and for safeguarding the health status of peri-implant tissue over a 3-month administration period. |
| Databáze: | OpenAIRE |
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