Necrotizing Glomerulonephritis and Pulmonary Hemorrhage Associated with Carbimazole Therapy
| Autor: | Fernando López-Rubio, Alfonso Calañas-Continente, Mario Espinosa, Pedro Aljama, Rafael Santamaria, Gregorio Manzano-García |
|---|---|
| Rok vydání: | 2005 |
| Předmět: |
Lung Diseases
endocrine system medicine.medical_specialty endocrine system diseases Carbimazole Endocrinology Diabetes and Metabolism Arthritis Hemorrhage Kidney Necrosis Glomerulonephritis Endocrinology Pharmacotherapy Antithyroid Agents immune system diseases medicine Humans skin and connective tissue diseases Adverse effect business.industry Middle Aged medicine.disease Dermatology Rash Graves Disease Treatment Outcome Creatinine Immunology Female Radiography Thoracic Pulmonary hemorrhage Propylthiouracil medicine.symptom business Vasculitis hormones hormone substitutes and hormone antagonists medicine.drug |
| Zdroj: | Thyroid. 15:286-288 |
| ISSN: | 1557-9077 1050-7256 |
| DOI: | 10.1089/thy.2005.15.286 |
| Popis: | Methimazole, carbimazole, and propylthiouracil (PTU) are the mainstays of antithyroid drug therapy. Adverse effects of these drugs have been documented in less than 15% of patients undergoing treatment for hyperthyroidism. Common problems include fever, skin rash, urticaria, arthralgias, and arthritis. Vasculitis associated with antineutrophil anticytoplasmic antibodies (ANCA) has been reported on several occasions following treatment with PTU. However, vasculitis rarely appears to be associated with carbimazole. We report the clinical history of a woman with a necrotizing glomerulonephritis and pulmonary hemorrhage associated with carbimazole therapy. |
| Databáze: | OpenAIRE |
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