Magnetically Aligned Nanorods in Alginate Capsules (MANiACs): Soft Matter Tumbling Robots for Manipulation and Drug Delivery
| Autor: | Sagar Chowdhury, J. Watson-Daniels, Chenghao Bi, Sahar Jafari, Olivia Hale, Shailesh B. Raval, Danica Sun, Dian R. Arifin, Benjamin A. Evans, Maria Guix, James Baker-McKee, Jeff W.M. Bulte, Bradley English, Chad Ropp, Lamar O. Mair, Pavel Stepanov, Benjamin V. Johnson, Genaro A. Paredes-Juarez, Irving N. Weinberg, Zachary Baker, David J. Cappelleri |
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| Rok vydání: | 2019 |
| Předmět: |
Materials science
Biocompatibility surface walkers lcsh:Mechanical engineering and machinery Nanotechnology 02 engineering and technology 010402 general chemistry magnetic microrobots 01 natural sciences Article tumbling robots Drug encapsulation lcsh:TJ1-1570 alginate capsules Soft matter Electrical and Electronic Engineering magnetic nanorods rotating magnetic fields Mechanical Engineering 021001 nanoscience & nanotechnology Biocompatible material 0104 chemical sciences Control and Systems Engineering Drug delivery Robot Nanorod 0210 nano-technology micromanipulation |
| Zdroj: | Micromachines Volume 10 Issue 4 Micromachines, Vol 10, Iss 4, p 230 (2019) |
| ISSN: | 2072-666X |
| Popis: | Soft, untethered microrobots composed of biocompatible materials for completing micromanipulation and drug delivery tasks in lab-on-a-chip and medical scenarios are currently being developed. Alginate holds significant potential in medical microrobotics due to its biocompatibility, biodegradability, and drug encapsulation capabilities. Here, we describe the synthesis of MANiACs&mdash Magnetically Aligned Nanorods in Alginate Capsules&mdash for use as untethered microrobotic surface tumblers, demonstrating magnetically guided lateral tumbling via rotating magnetic fields. MANiAC translation is demonstrated on tissue surfaces as well as inclined slopes. These alginate microrobots are capable of manipulating objects over millimeter-scale distances. Finally, we demonstrate payload release capabilities of MANiACs during translational tumbling motion. |
| Databáze: | OpenAIRE |
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