Additional file 7 of Optogenetically controlled human functional motor endplate for testing botulinum neurotoxins

Autor: de Lamotte, Juliette Duchesne, Polentes, J��r��me, Roussange, Florine, Lesueur, L��a, Feurgard, Pauline, Perrier, Anselme, Nicoleau, Camille, Martinat, C��cile
Rok vydání: 2021
DOI: 10.6084/m9.figshare.17127348.v1
Popis: Additional file 7: Figure S7. BoNTs effects on another line of motor neurons (56c2) connected to muscle cells and optogenetically controlled. Quantification of Ca2+ oscillations after rBoNT/A (5 nM or 0.0016 nM), mBoNT (5 nM or 0.0016 nM) or no BoNT exposure, before (pre-stim) and after (post-stim) red light stimulation over the time. Recordings were performed before treatment (basal), 4 h (H + 4) and 8 h (H + 8) after exposure of BoNTs or no treatment. Data are represented as mean �� SEM (N = 3). ANOVA with Sidak���s post hoc tests (****p
Databáze: OpenAIRE