Current Issues in Carcinogenesis
Autor: | I.V. Vysotskaya, VYu Kirsanov, Ea Kim, N.V. Levkina, MA Shabanov, V.P. Letyagin |
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Jazyk: | ruština |
Rok vydání: | 2018 |
Předmět: |
0301 basic medicine
business.industry Hematology promotion proto-oncogenes medicine.disease_cause targeted therapy lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens lcsh:RC254-282 initiation suppressor genes 03 medical and health sciences 030104 developmental biology 0302 clinical medicine Oncology repair Cancer research Medicine TP53 Current (fluid) business Carcinogenesis carcinogenesis 030217 neurology & neurosurgery Ras |
Zdroj: | Kliničeskaâ onkogematologiâ, Vol 12, Iss 1, Pp 101-106 (2018) |
ISSN: | 2500-2139 1997-6933 |
Popis: | The review presents current data on the major pathogenetic mechanisms underlying uncontrolled growth and dissemination of tumor and its resistance to conventional treatment. Cell genetic instability associated with accumulation of mutations in genes controlling cell growth and differentiation is a key factor in tumor proliferation. Due understanding and detailed analysis of carcinogenesis processes provide the basis for creation of new anticancer drugs which in turn enables optimization and individualization of cancer treatment. |
Databáze: | OpenAIRE |
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