Anti-activated factor × response to enoxaparin in critically ill patients

Autor: Moshe Hersch, D Shemesh, D Bitran, M Naamad, Shoshana Zevin, Sharon Einav, I Dezigibker
Jazyk: angličtina
Rok vydání: 2009
Předmět:
Zdroj: Critical Care
ISSN: 1466-609X
1364-8535
Popis: Low molecular weight heparin (LMWH) dosing protocols for deep vein thrombosis prophylaxis in critically ill patients (CIPs) are not based on pharmacologic studies in these patients. Antithrombotic LMWH activity correlates with peak anti-activated factor × (aFXa) levels (4 hours post injection) of 0.1 to 0.2 IU/ml. The hypothesis of this study is that most CIPs do not achieve therapeutic levels for prevention of DVT.
Databáze: OpenAIRE