Branch Pulmonary Artery Regurgitation in Repaired Tetralogy of Fallot: Correlation with Pulmonary Artery Morphology, Distensibility, and Right Ventricular Function
| Autor: | Apichaya Sriprachyakul, Suvipaporn Siripornpitak, Alisa Limsuwan, Suthep Wanitkun, Duangkanok Lueangwattanapong |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Adolescent Computer applications to medicine. Medical informatics R858-859.7 Pulmonary insufficiency Regurgitation (circulation) Pulmonary Artery branch pulmonary artery Article repaired tetralogy of Fallot Interquartile range Internal medicine medicine.artery medicine Humans Radiology Nuclear Medicine and imaging Tetralogy of Fallot medicine.diagnostic_test business.industry regurgitation fraction pulmonary distensibilty Magnetic resonance imaging Odds ratio medicine.disease Magnetic Resonance Imaging Pulmonary Valve Insufficiency Confidence interval right ventricular function Pulmonary artery Ventricular Function Right Cardiology business |
| Zdroj: | Tomography Tomography, Vol 7, Iss 36, Pp 412-423 (2021) Volume 7 Issue 3 Pages 36-423 |
| ISSN: | 2379-139X |
| DOI: | 10.3390/tomography7030036 |
| Popis: | Background: The aim was to determine the effect of pulmonary artery (PA) morphology on the branch pulmonary artery-regurgitation fraction (BPA-RF), the relationship of pulmonary insufficiency (PI) to BPA-RF and PA-distensibility, and factors (BPA-RF and PA-distensibility) associated with right ventricular function (RVF) in repaired tetralogy of Fallot (rTOF). Methods: A total of 182 rTOF patients (median age 17.1 years) were analyzed for length, angle of PA, BPA-RF, PI, and PA-distensibility, using magnetic resonance imaging. Results: The left PA had a significant greater RF than the right PA (median (interquartile range)): LPA 43.1% (32.6–51.5) and RPA 35.2% (24.7–44.7), p < 0.001. The LPA was shorter with a narrower angle than the RPA (p < 0.001). The anatomy of the branch-PA was not a factor for the greater LPA-RF (odds ratio, 95% confidence interval: CI, p-value): length 0.44 (0.95–2.00), p = 0.28 angle 0.63 (0.13–2.99), p = 0.56. There was a strong positive correlation between PI and BPA-RF-coefficients (95% CI), p-value: LPA 0.78% (0.70–0.86), p < 0.001 RPA 0.78% (0.71–0.84), p < 0.001 and between BPA-RF and distensibility-coefficients (95%CI), p-value: LPA 0.73% (0.37–1.09), p < RPA 1.63% (1.22–2.03), p < 0.001, respectively. The adjusted BPA-RF did not predict RVF, RPA (p = 0.434), LPA (p = 0.268). Conclusions: PA morphology is not a significant factor for the differential BPA-RF. The vascular wall in rTOF patients responds to chronic increased intravascular volume by increasing distensibility. BPA-RF is not a determinant of RVF. |
| Databáze: | OpenAIRE |
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