The influence of chloroquine on the formation of porphyrins by yeasts

Autor:	Kotal P, J. Vernerová, V. Kordač, Milan Jirsa
Rok vydání:	1984
Předmět:	Cellular membrane Porphyrins Chemistry Cell Membrane Chloroquine Saccharomyces cerevisiae Permeation Models Biological Biochemistry Cell membrane medicine.anatomical_structure polycyclic compounds medicine heterocyclic compounds Intracellular medicine.drug
Zdroj:	International Journal of Biochemistry. 16:1087-1090
ISSN:	0020-711X
DOI:	10.1016/0020-711x(84)90093-4
Popis:	A single two-compartment model suitable for studying the production and elimination of porphyrins from cells was prepared. Chloroquine with increasing concentrations:-- Inhibits the total production of porphyrins. Reduces intracellular concentration of porphyrins. Increases transversal permeation of porphyrins through the cellular membrane.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ef482e68ff29516f047d30c7d761e68 https://doi.org/10.1016/0020-711x(84)90093-4 Zobrazit plný text záznamu