Evaluation of a rapid immunodiagnostic test kit for detection of African lyssaviruses from brain material
| Autor: | K. le Roux, Wonderful Shumba, Louis Hendrik Nel, G.C. Zulu, D. York, Wanda Markotter, Claude T. Sabeta |
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| Předmět: |
Genotype
Rabies Virulence Fluorescent Antibody Technique rabies Biology Mice rapid test Rhabdoviridae Infections diagnostics Animals Direct fluorescent antibody Lyssavirus lcsh:Veterinary medicine General Veterinary Brain General Medicine lyssavirus biology.organism_classification Virology Rabies virus Africa biology.protein lcsh:SF600-1100 Antibody |
| Zdroj: | Scopus-Elsevier Onderstepoort Journal of Veterinary Research, Vol 76, Iss 2, Pp 257-262 (2009) Onderstepoort Journal of Veterinary Research, Volume: 76, Issue: 2, Pages: 257-262, Published: 2009 |
| Popis: | Rapid immunodiagnostic test kit was evaluated against a selection of isolates of lyssavirus genotypes occurring in Africa. The test was carried out in parallel comparison with the fluorescent antibody test (FAT) and isolates representing previously established phylogenetic groups from each genotype were included. The specificity of the rapid immunodiagnostic test compared favourably with the FAT and was found to detect all representatives of genotypes 1, 2, 3 and 4 in brain samples of either field cases or suckling mouse brain inoculates. |
| Databáze: | OpenAIRE |
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