Supplementary Figures 1-5 from Genome-wide DNA Methylation Events in TMPRSS2–ERG Fusion-Negative Prostate Cancers Implicate an EZH2-Dependent Mechanism with miR-26a Hypermethylation

Autor: Michal R. Schweiger, Hans Lehrach, Holger Sültmann, Thorsten Schlomm, Guido Sauter, Mark A. Rubin, Francesca Demichelis, Ronald Simon, Markus Graefen, Christoph Plass, Rainer Claus, Bernd Timmermann, Andrea Wunderlich, Christina Röhr, Melanie Isau, Behnam Sayanjali, Christina Grimm, Andreas Dahl, Ruprecht Kuner, Jan C. Brase, Mark Laible, Maria Fälth, Martin Kerick, Axel Fischer, Stefan T. Börno
Rok vydání: 2023
DOI: 10.1158/2159-8290.22528505.v1
Popis: PDF file - 947K, Supplementary Fig. S1. Differential methylations in PCa validated by BS-MS experiments. Supplementary Fig. S2. DNA-Methylomes of prostate cancer differ significantly from normal tissues. Supplementary Fig. S3. Global differences in DNA methylation patterns between tumor, normal, FUS+ and FUS- samples. Supplementary Fig. S4 Patientwise patterns of promoter hypermethylation and corresponding gene expression of EZH2 target genes. Supplementary Fig. S5 Methylation of the miRNA-26a genomic region
Databáze: OpenAIRE