MMN and P300 are both modulated by the featured/featureless nature of deviant stimuli
| Autor: | Paul Deltenre, Cécile Colin, Ingrid Hoonhorst, Axelle Calcus, Gregory Collet, Emily Markessis |
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| Rok vydání: | 2015 |
| Předmět: |
Adult
Male medicine.medical_specialty Dissociation (neuropsychology) Mismatch negativity Audiology behavioral disciplines and activities Young Adult P3a Physiology (medical) P3b Reaction Time medicine Humans Sensory memory Deviant stimulus Event-Related Potentials P300 Sensory Systems Behavioral data Acoustic Stimulation Neurology Evoked Potentials Auditory Female Neurology (clinical) Psychology Social psychology Psychomotor Performance |
| Zdroj: | Clinical Neurophysiology. 126:1727-1734 |
| ISSN: | 1388-2457 |
| DOI: | 10.1016/j.clinph.2014.11.020 |
| Popis: | Objective This study was designed to test the effect of the featured/featureless nature of deviant stimuli on mismatch negativity (MMN), P300 (P3a and P3b) and on behavioral discrimination performances. Methods Ten healthy adults were submitted to stimuli contrasted by the presence or absence of a frequency sweep. Discrimination performances were collected during the neurophysiological sessions. Results MMN, P3a and P3b were much larger for featured deviants than for featureless ones. Behavioral data ( d ', at ceiling level, and reaction times) were not affected by the featured/featureless nature of the deviant stimulus. Conclusion Behavioral results and MMN amplitudes are in accordance with our previous study, using the same design albeit in an ignore condition and with collection of the behavioral data deferred until after the neurophysiological sessions. The present study strengthens previous evidence suggesting that two mechanisms contribute to the MMN evoked by featured deviants: the memory comparison process and the adaptation/fresh-afferent phenomenons. Significance We here demonstrate that the neurophysiological processes underlying P300 generation are also impacted by the featured/featureless nature of the deviant stimulus and that the dissociation from behavioral data, which are not impacted, is also observed when both types of data are recorded simultaneously. |
| Databáze: | OpenAIRE |
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