Treatment of Behçet's disease with granulocyte and monocyte adsorption apheresis
| Autor: | Ryoko Sakamoto, Masahiro Iwata, Takuro Kanekura, Seita Fukumaru, Tamotsu Kanzaki, Ikuro Maruyama, Akira Gushi, Ko-ichi Kawahara |
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| Rok vydání: | 2004 |
| Předmět: |
Adult
Male Systemic disease Abdominal pain medicine.medical_specialty Neutrophils Macrophage-1 Antigen Dermatology Behcet's disease Monocytes Medicine Humans Pain Measurement business.industry Vascular disease Monocyte Behcet Syndrome Remission Induction Middle Aged medicine.disease Flow Cytometry digestive system diseases Surgery Genital ulcer medicine.anatomical_structure Apheresis Blood Component Removal Female Adsorption medicine.symptom business Vasculitis Granulocytes |
| Zdroj: | Journal of the American Academy of Dermatology. 51 |
| ISSN: | 1097-6787 |
| Popis: | The painful orogenital ulcerations of Behcet's disease are among the major symptoms of patients and are often intractable. We assessed the efficacy of granulocyte and monocyte adsorption apheresis therapy in two patients, a 21-year-old man with orogenital ulcerations and a 50-year-old woman with genital ulceration and abdominal pain. They underwent 5 and 8 granulocyte and monocyte adsorption apheresis treatments at 5-day intervals, respectively. The painful orogenital ulcerations of the man responded dramatically and the genital ulcer of the woman decreased in size and her abdominal pain was improved. Our results demonstrate that granulocyte and monocyte adsorption apheresis may be useful for treating orogenital ulcerations of Behcet's disease. |
| Databáze: | OpenAIRE |
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