β -Thalassaemia and its Co-existence with Haemoglobin E and Haemoglobin S in Upper Assam Region of North Eastern India: A Hospital Based Study
| Autor: | Sidhartha Protim Saikia, Rumi Deori, Rashmi Rajkakati, Rita Panyang, Anju Barhai Teli, Kalyani Pathak |
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| Rok vydání: | 2016 |
| Předmět: |
congenital
hereditary and neonatal diseases and abnormalities Veterinary medicine complete blood count Haemoglobin s 030231 tropical medicine Clinical Biochemistry lcsh:Medicine hplc β thalassaemia Genetics Section Hospital based study 03 medical and health sciences 0302 clinical medicine hemic and lymphatic diseases parasitic diseases medicine 030212 general & internal medicine anaemia medicine.diagnostic_test business.industry Incidence (epidemiology) lcsh:R Complete blood count General Medicine Thalassaemias Eastern india Indian subcontinent business |
| Zdroj: | Journal of Clinical and Diagnostic Research, Vol 10, Iss 4, Pp GC01-GC04 (2016) |
| ISSN: | 2249-782X |
| DOI: | 10.7860/jcdr/2016/16265.7675 |
| Popis: | Introduction β-Thalassaemias are common genetic disorders in the Indian subcontinent and its status has not been well studied in the Upper Assam region of North Eastern India. Aim The aim of the study was to show the prevalence of β- thalassaemias and its co-existence with Haemoglobin E and Haemoglobin S in the Upper Assam region of North Eastern India. Materials and methods A total of 1200 anaemic patients were investigated for β- thalassaemias. Complete Blood Count (CBC) and High Performance Liquid Chromatography (HPLC) were done for screening. Results Out of 1200 patients screened, 5.83% β-thalassaemia trait, 2.33% compound Hb E/β-Thalassaemia, 1.33% β-thalassaemia major and 0.42% compound Hb S/β- thalassaemia were detected. A high incidence of thalassaemia is found among the people of Upper Assam region of North Eastern India. Conclusion The only way to prevent the disease is carrier detection and awareness among the people about it. |
| Databáze: | OpenAIRE |
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