Intraneural Hybrid Neurofibroma/ Schwannoma In Scalp: A Case Report
| Autor: | Naik Reena, Kishori Moni Panda |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
Pathology
medicine.medical_specialty business.industry Clinical Biochemistry lcsh:R lcsh:Medicine Histology General Medicine Schwannoma medicine.disease medicine.anatomical_structure Scalp Pathology Section otorhinolaryngologic diseases Medicine Neurofibroma Immunohistochemistry pathology Neurofibromatosis business Schwannomatosis Peripheral Nerve Sheath ihc bpnst |
| Zdroj: | Journal of Clinical and Diagnostic Research, Vol 9, Iss 10, Pp ED05-ED06 (2015) |
| Popis: | Benign Peripheral Nerve Sheath Tumours (BPNSTs) are traditionally classified into schwannoma, neurofibroma and perinurioma. Due to advances in molecular techniques, hybrid BPNSTs containing more than one histologic types have been documented. Recent studies have demonstrated their frequent association with inherited syndromes like schwannomatosis and neurofibromatosis. Intraneural variant of hybrid neurofibroma/schwannoma is yet to be described. Here we report such a case in a 30-year-old male, who presented with a scalp swelling and histology showed intraneural neurofibromatous tumour admixed with schwannoma-like nodules. IHC (immunohistochemistry) showed variable S100 staining in neurofibromatous areas, diffuse S100 staining in schwannoma-like areas and negative EMA staining in the tumour. |
| Databáze: | OpenAIRE |
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