Application of Contrast-Enhanced 3-Dimensional T2-Weighted Volume Isotropic Turbo Spin Echo Acquisition Sequence in the Diagnosis of Prolactin-Secreting Pituitary Microadenomas
| Autor: | Haiyang Zhou, Yunping Xiao, Shoutang Liu, Yue Wu, Guangcheng Guo, Rui Guo, Zhenwei Yao |
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| Rok vydání: | 2022 |
| Předmět: |
Adenoma
Adult Male Adolescent media_common.quotation_subject Neuroimaging: Brain pituitary adenoma Young Adult Nuclear magnetic resonance Imaging Three-Dimensional Image Interpretation Computer-Assisted Contrast (vision) Medicine Humans Radiology Nuclear Medicine and imaging Pituitary Neoplasms dynamic contrast-enhanced MRI volume isotropic turbo spin echo acquisition sequence Sequence (medicine) media_common Aged business.industry Isotropy Fast spin echo Middle Aged Magnetic Resonance Imaging Prolactin Hyperprolactinemia Pituitary Gland ComputingMethodologies_DOCUMENTANDTEXTPROCESSING Female T2 weighted business Volume (compression) MRI |
| Zdroj: | Journal of Computer Assisted Tomography |
| ISSN: | 1532-3145 |
| Popis: | Supplemental digital content is available in the text. Objective This study aimed to investigate the value of contrast-enhanced 3-dimensional (3D) T2-weighted (T2W) Volume Isotropic Turbo Spin Echo Acquisition (VISTA) sequence in prolactin-secreting pituitary adenoma diagnosis. Methods We enrolled 158 patients with hyperprolactinemia. Coronal dynamic contrast-enhanced (DCE) T1 spin echo and T2W VISTA sequences were performed. The detection of pituitary microadenomas in 3 imaging groups (DCE magnetic resonance imaging [MRI], VISTA, and DCE MRI + VISTA) were compared using McNemar test and χ2 test. Results The DCE MRI + VISTA group detected 28 more pituitary microlesions than DCE MRI alone. Among these, 20 lesions were clearly observed on VISTA images but were negative on DCE MRI. The combined sequences showed higher sensitivity (85.3%) and diagnostic accuracy (89.2%) for adenoma detection than any of the sequences alone (P < 0.01). We noted that in 65.7% of the patients with adenoma (46 of 70), a “hypointense rim” was present around the lesion on the VISTA images. Of them, 11 patients underwent surgery. Histopathology confirmed that the “hypointense rim” was a pseudocapsular structure at the edge of the adenoma. Conclusions For patients with hyperprolactinemia, the 3D T2W VISTA sequence is an important supplement to DCE MRI, because it could improve the detection rate of pituitary microadenomas. |
| Databáze: | OpenAIRE |
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