Clinicopathological study of breast tissue in female-to-male transsexuals
| Autor: | Shinji Itoyama, Hajime Kuroda, Goi Sakamoto, Kiyoshi Ohnisi |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
Adult
medicine.medical_specialty Gender Identity Disorder Adolescent medicine.drug_class Mammary gland Physiology urologic and male genital diseases Young Adult Surgical oncology medicine Humans Breast Young adult Gynecology Hyperplasia business.industry General Medicine Middle Aged Androgen medicine.disease Transsexual Carcinoma Intraductal Noninfiltrating medicine.anatomical_structure Androgen Therapy Androgens Female Surgery business Transsexualism |
| Zdroj: | Surgery Today. 38:1067-1071 |
| ISSN: | 1436-2813 0941-1291 |
| Popis: | Gender identity disorder is defined as persistent feelings of gender discomfort and the inappropriateness of one's anatomical sex. To study the effects of androgens on female breast tissue, we examined mammary glands from female-to-male transsexual (FTMT) women using androgen therapy and from those not using androgen therapy.Female-to-male transsexual breast tissue is a rare specimen in surgical pathology and there are no well-defined guidelines for its examination. We evaluated the clinicopathologic findings of 186 FTMT mammary glands.The patients' ages at presentation ranged from 18 to 49 years (mean 27.4 years). We detected breast carcinoma in only 1 of 130 FTMT women who had not used androgen therapy and in none of 56 FTMT women who had used androgen therapy.We described the histopathological morphology of FTMT breast tissue. The frequency of carcinoma and hyperplasia did not differ significantly between FTMT women who had used androgen therapy and those who had not. These findings suggest that androgen does not alter the risk of carcinoma developing in the mammary glands of FTMT women. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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