A Critical Appraisal of Growth Hormone Therapy in Growth Hormone Deficiency and Turner Syndrome Patients in Turkey
Autor: | Feyza Darendeliler, Neyzi O, Yavaş Abalı Z |
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Rok vydání: | 2016 |
Předmět: |
Pediatrics
medicine.medical_specialty Turkey Turner syndrome Endocrinology Diabetes and Metabolism Treatment outcome 030209 endocrinology & metabolism Growth hormone Short stature Growth hormone deficiency 03 medical and health sciences 0302 clinical medicine Endocrinology 030225 pediatrics medicine Humans Dosing Child Growth Disorders Dose-Response Relationship Drug business.industry Brief Report medicine.disease Critical appraisal Early Diagnosis Treatment Outcome Growth Hormone Pediatrics Perinatology and Child Health Female medicine.symptom business GH Deficiency |
Zdroj: | Journal of Clinical Research in Pediatric Endocrinology |
ISSN: | 1308-5727 |
DOI: | 10.4274/jcrpe.3209 |
Popis: | Early detection of abnormal growth, identification of the underlying cause, and appropriate treatment of the medical condition is an important issue for children with short stature. Growth hormone (GH) therapy is widely used in GH-deficient children and also in non-GH-deficient short stature cases who have findings conforming to certain indications. Efficacy of GH therapy has been shown in a multitude of short- and long-term studies. Age at onset of GH therapy is the most important factor for a successful treatment outcome. Optimal dosing is also essential. The aim of this review was to focus on challenges in the early diagnosis and appropriate management of short stature due to GH deficiency (GHD) and Turner syndrome. These are the most frequent two indications for GH therapy in Turkey approved by the Ministry of Health for coverage by the national insurance system. |
Databáze: | OpenAIRE |
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