Coexistence of childhood absence epilepsy and benign epilepsy with centrotemporal spikes: A case series
| Autor: | Federico Mecarini, Giancarlo Di Gennaro, Pasquale Parisi, Victoria Elisa Rinaldi, Anthony J. Ritaccio, Renato D'Alonzo, Sara Casciato, Pasquale Striano, Nelia Zamponi, Salvatore Savasta, Marco Carotenuto, Alberto Verrotti, Alberto Spalice |
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| Přispěvatelé: | Verrotti, Alberto, Casciato, Sara, Spalice, Alberto, Carotenuto, Marco, Striano, Pasquale, Parisi, Pasquale, Zamponi, Nelia, Savasta, Salvatore, Rinaldi, Victoria Elisa, D'Alonzo, Renato, Mecarini, Federico, Ritaccio, Anthony J., Di Gennaro, Giancarlo |
| Rok vydání: | 2016 |
| Předmět: |
Childhood epilepsy
Male Pediatrics medicine.medical_specialty Benign epilepsy with centrotemporal spikes (BECTS) Idiopathic generalized epilepsy pediatrics Adolescent Absence seizures benign epilepsy with centrotemporal spikes (BECTS) childhood absence epilepsy (CAE) idiopathic generalized epilepsy adolescent child epilepsy absence epilepsy rolandic female humans male Prognosis pediatrics perinatology and child Health neurology (clinical) Anticonvulsant therapy Absence seizure 030218 nuclear medicine & medical imaging 03 medical and health sciences Epilepsy 0302 clinical medicine Childhood absence epilepsy Medicine Humans absence Childhood absence epilepsy (CAE) Child business.industry General Medicine rolandic medicine.disease Epilepsy Rolandic Epilepsy Absence Anesthesia Benign epilepsy Pediatrics Perinatology and Child Health epilepsy Female perinatology and child Health Good prognosis Neurology (clinical) Age of onset business 030217 neurology & neurosurgery |
| Zdroj: | European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society. 21(3) |
| ISSN: | 1532-2130 |
| Popis: | Aim Childhood absence epilepsy (CAE) and benign childhood epilepsy with centrotemporal spikes (BECTS) are the most common forms of childhood epilepsy. Recent studies in animal models suggest that the two phenotypes may represent a neurobiological continuum. Although the coexistence of CAE and BECTS has been reported, this issue remains controversial. The purpose of this study was to analyse the electro-clinical characteristics of a group of children with contemporary or subsequent features of absence seizures and focal seizures consistent with BECTS. Material and methods A systematic record review from 8 epilepsy centres was used to identify 11 subjects, 5 females and 6 males, with electro-clinical documented consecutive or contemporary coexistence of CAE and BECTS. Results Patient's age ranged between 7.8 and 17.3 years. Four out of 11 patients presented concomitant features of both syndromes, whereas the remaining 7 experienced the two syndromes at different times. Conclusions Although CAE and BECTS are clearly defined syndromes and considered very different in terms of their pathophysiology, they share some features (such as similar age of onset, overall good prognosis), and can occur in the same patient. The long term prognosis of these patients seems to be good with an excellent response to anticonvulsant therapy. |
| Databáze: | OpenAIRE |
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