Delayed diagnosis and inappropriate clinical management of nicorandil-induced oral lesions: A case report
| Autor: | Carle Favre de Thierrens, Marie De Boutray, Céline Girard, JH Torres, MA Fauroux, Sarah Takadoum |
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| Přispěvatelé: | Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), Université de Montpellier (UM) |
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Side effect [SDV]Life Sciences [q-bio] Delayed diagnosis Pathology and Forensic Medicine 03 medical and health sciences 0302 clinical medicine Medicine Radiology Nuclear Medicine and imaging Dentistry (miscellaneous) Medical history Oral ulcers Oral mucosa Nicorandil business.industry 030206 dentistry Dermatology 3. Good health Discontinuation medicine.anatomical_structure 030220 oncology & carcinogenesis cardiovascular system Etiology Surgery Oral Surgery business medicine.drug |
| Zdroj: | Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, New York, NY : Elsevier, 2020, 130, pp.e324-e327. ⟨10.1016/j.oooo.2020.06.006⟩ |
| ISSN: | 2212-4403 |
| Popis: | Oral ulcers have a number of causes, and as a result, their etiology can be difficult to determine. Clinical management can range from simple treatment of the symptoms to extensive surgical excision, as in the case of malignant ulcers. Nicorandil, an antiangina drug, has been identified as a potential trigger for cutaneomucosal ulcers. This article reviews the importance of taking a full medical history when seeking to identify the side effects of treatments. We present the case of a 70-year-old patient with chronic ulceration of the oral mucosa. Determining the cause of ulceration as a side effect of taking nicorandil was delayed because the team that initially managed the patient hypothesized a malignant etiology. As a result, a partial glossectomy was performed for diagnostic and therapeutic purposes. After extensive examination of the patient's medical history and current treatments, nicorandil was identified as the potential trigger. The patient finally recovered after discontinuation of nicorandil. |
| Databáze: | OpenAIRE |
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