A case of tick-borne encephalitis in Japan and isolation of the the virus
Autor: | Daisuke Hayasaka, Chikako Takezawa, Hiroaki Kariwa, Nobuo Hashimoto, Jiro Arikawa, Tatsuro Sato, Misako Chiba, Kumiko Yoshimatsu, Ikuo Takashima, Akira Igarashi, Kouichi Morita |
---|---|
Rok vydání: | 1997 |
Předmět: |
Microbiology (medical)
Molecular Sequence Data Enzyme-Linked Immunosorbent Assay Virus Encephalitis Viruses Tick-Borne Serology Flaviviridae Dogs Antibody Specificity medicine Encephalitis Viruses Animals Humans Dog Diseases biology Tick-borne encephalitis Antibodies Monoclonal medicine.disease biology.organism_classification Virology Tick-borne encephalitis virus Flavivirus Female Sentinel Surveillance Encephalitis Tick-Borne Encephalitis Research Article |
Zdroj: | Journal of Clinical Microbiology. 35:1943-1947 |
ISSN: | 1098-660X 0095-1137 |
Popis: | A case of tick-borne encephalitis (TBE) has not been reported for many years in Japan, although a serological survey of sera from domestic animals suggested the presence of TBE foci in Hokkaido, the northern island of Japan. Studies were conducted to prove the presence of an endemic focus of TBE virus in Japan by means of serology and virus isolation. In October 1993 in Hokkaido, a severe case of encephalitis in a dairy farmer's wife was diagnosed as TBE. Serological examination of paired serum specimens showed a rise in the neutralization antibody titer to Russian spring summer encephalitis virus. A seroepizootiological survey of dogs showed that the TBE-related virus was prevalent in the area. Three virus isolates were obtained from the blood of sentinel dogs, and antigenic analysis grouped the isolates into TBE-related viruses. Sequence analysis of the envelope protein gene identified one of the isolates as being of the same subtype as the Russian spring summer encephalitis (Far Eastern TBE) virus. The results provide evidence that TBE is endemic in a certain area of Japan. |
Databáze: | OpenAIRE |
Externí odkaz: |