Cotard syndrome in anti-NMDAR encephalitis: two patients and insights from molecular imaging

Autor:	P Bustamante-Gomez, J Ramirez Bermúdez, IE Dias Meneses, M Espínola-Nadurille, M Restrepo-Martinez, Mario F. Mendez, Nora E. Kerik
Rok vydání:	2021
Předmět:	Pathology medicine.medical_specialty Cotard syndrome Delusions 050105 experimental psychology 03 medical and health sciences 0302 clinical medicine Arts and Humanities (miscellaneous) Fluorodeoxyglucose F18 medicine Humans 0501 psychology and cognitive sciences Anti-N-Methyl-D-Aspartate Receptor Encephalitis Autoimmune encephalitis business.industry 05 social sciences Nihilistic delusions Anti-NMDAR Encephalitis medicine.disease Molecular Imaging nervous system Positron-Emission Tomography Neurology (clinical) business 030217 neurology & neurosurgery Encephalitis
Zdroj:	Neurocase. 27:64-71
ISSN:	1465-3656 1355-4794
Popis:	Cotard syndrome is a clinical condition defined by the presence of nihilistic delusions. We report two patients with Cotard syndrome in whom anti-NMDAR encephalitis (ANMDARE) was confirmed. Both cases showed features of affective psychosis, developed catatonic syndrome, and worsened after the use of antipsychotics. 18F-FDG PET brain studies showed a bilateral hemispheric pattern of hypometabolism in posterior regions, mainly in the cingulate cortex and in the medial aspects of parietal and occipital lobes. A more severe hypometabolism was observed in the right hemisphere of both patients. Both cases remitted with the use of specific immunotherapy for ANMDARE.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7eaae058e2bc34e83e5177923d88e976 https://doi.org/10.1080/13554794.2020.1866018 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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