Baseline IOP predicts selective laser trabeculoplasty success at 1 year post-treatment: results from a randomised clinical trial
| Autor: | A.M. Bovell, Karim F. Damji, William J. Rock, William G. Hodge, Ralf Buhrmann, Y.I. Pan |
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| Rok vydání: | 2005 |
| Předmět: |
Adult
Male Intraocular pressure medicine.medical_specialty Trabeculoplasty Randomization genetic structures Selective laser trabeculoplasty Open angle glaucoma medicine.medical_treatment Glaucoma Trabeculectomy Clinical Science - Extended Reports Cellular and Molecular Neuroscience Ophthalmology medicine Humans Intraocular Pressure Aged Aged 80 and over Chi-Square Distribution business.industry Middle Aged Prognosis medicine.disease eye diseases Sensory Systems Clinical trial medicine.anatomical_structure Female Laser Therapy sense organs Trabecular meshwork business Glaucoma Open-Angle |
| Zdroj: | British Journal of Ophthalmology. 89:1157-1160 |
| ISSN: | 0007-1161 |
| DOI: | 10.1136/bjo.2004.062414 |
| Popis: | Background/aims: The efficacy and safety of selective laser trabeculoplasty (SLT) has been found to be equivalent to argon laser trabeculoplasty (ALT). Since SLT produces significantly less disturbance to the trabecular meshwork and is theoretically more repeatable than ALT, it has potential to replace ALT as the standard procedure to treat medically uncontrolled open angle glaucoma. This study’s objective is to determine factors that predict successful SLT at 1 year post-treatment. Methods: As part of a randomised clinical trial comparing the efficacy and safety of SLT to ALT, data on 72 SLT patients were collected, and successful SLT defined as having an SLT induced intraocular pressure (IOP) reduction of ⩾20% at 1 year post-treatment follow up. Results: 43 out of the 72 patients who had completed their 1 year follow up visit had an IOP reduction of ⩾20% from baseline. No glaucoma risk factors studied predicted successful SLT. The amount of trabecular meshwork pigmentation was not a significant predictor. However, it was discovered that baseline IOP strongly predicted SLT success (odds ratio = 1.16; p = 0.0001). Conclusion: SLT success was significantly predicted by baseline IOP but not by age, sex, other glaucoma risk factors, type of open angle glaucoma, or by degree of trabecular meshwork pigmentation. |
| Databáze: | OpenAIRE |
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