Reaction time slowing in HIV-1-infected individuals: Role of the preparatory interval
Autor: | E. D. Nannis, W. A. Law, L. R. Temoshok, R. L. Mapou, T. L. Roller, Alex Martin |
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Rok vydání: | 1995 |
Předmět: |
Adult
Male Oncology medicine.medical_specialty Time Factors Human immunodeficiency virus (HIV) medicine.disease_cause Developmental psychology Acquired immunodeficiency syndrome (AIDS) HIV Seronegativity Internal medicine Reaction Time medicine Humans Visual attention Attention Sida Psychomotor learning Acquired Immunodeficiency Syndrome biology Choice reaction time Cognitive disorder virus diseases medicine.disease biology.organism_classification Affect Clinical Psychology Neurology HIV-1 Neurology (clinical) Viral disease Psychology Psychomotor Performance |
Zdroj: | Journal of Clinical and Experimental Neuropsychology. 17:122-133 |
ISSN: | 1744-411X 1380-3395 |
DOI: | 10.1080/13803399508406587 |
Popis: | Psychomotor speed and directed attention were evaluated in 83 human immunodeficiency virus-1-infected individuals (HIV+) and 50 HIV-1 seronegative (HIV-) control participants using simple and choice reaction time (RT) tasks. The simple RT task included 1- and 3-s, irregularly varied preparatory intervals (PI) between the warning and target lights. Relative to the HIV-group, simple and choice RT were significantly slowed in the HIV+ group. Further, again relative to the HIV- controls, the HIV+ group did not show expected faster RT with increased response preparation time in the simple RT task. This also occurred in some HIV+ subjects who did not have psychomotor slowing. These findings suggest that RT performance in HIV-1-infected individuals may reflect separate processes associated with psychomotor slowing and impaired ability to direct attention. Possible neural mechanisms associated with control of these processes are discussed. |
Databáze: | OpenAIRE |
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