Paraganglioma of the Urinary Bladder in a Dog

Autor: Shou-Ping, Hu, Zhuo, Zhang, Fei, Xiao, Jia-Ni, Huang, Yan, Jiang, Dong-Sheng, Mao, Jing-Fei, Wang, Xi-Jun, He
Rok vydání: 2022
Předmět:
Zdroj: Journal of Comparative Pathology. 195:1-6
ISSN: 0021-9975
Popis: A 3-year-old male Bichon Frise developed lethargy, anorexia and haematuria. B-scan ultrasonography examination revealed a small, irregular, soft-textured mass in the bladder. Histopathologically, there was an incomplete fibrous pseudocapsule around the tumour tissue and although there was clear demarcation from the surrounding tissue, there was invasion of the capsule. Tumour cells proliferated in nests or cords of variable size, separated by fibrovascular tissue. The neoplastic cells were immunopositive for chromogranin A, synaptophysin and neuron-specific enolase, and electron microscopy revealed that they contained cytoplasmic secretory granules. On the basis of these findings, the tumour was diagnosed as a primary paraganglioma of the urinary bladder.
Databáze: OpenAIRE