Direct influence of dexamethasone in vivo on rat testicular lipogenic enzymes involved in pyruvate-malate pathway
| Autor: | P. Govindarajulu, H. Mohammed Valivullah, M. Michael Aruldhas |
|---|---|
| Rok vydání: | 1983 |
| Předmět: |
Male
medicine.medical_specialty medicine.medical_treatment Biophysics Malic enzyme Malates Dehydrogenase Biology Biochemistry Malate dehydrogenase Dexamethasone Malate Dehydrogenase Internal medicine Pyruvic Acid Testis medicine Animals Pyruvates Molecular Biology chemistry.chemical_classification Adrenalectomy Rats Inbred Strains Cell Biology Lyase Isocitrate Dehydrogenase Rats Endocrinology Enzyme chemistry ATP Citrate (pro-S)-Lyase Specific activity medicine.drug |
| Zdroj: | Biochemical and biophysical research communications. 115(2) |
| ISSN: | 0006-291X |
| Popis: | Summary The changes in specific activities of NADP-isocitrate dehydrogenase, ATP-citrate lyase, Malate dehydrogenase and malic enzyme were studied in adrenalectomised and dexamethasone injected pubertal rats. One month after adrenalectomy the specific activity of NADP-isocitrate dehydrogenase increased but the specific activities of the other three enzymes decreased. An opposite effect was seen after dexamethasone administration to intact animals. The changes observed in the specific activities of enzymes of adrenalectomised and dexamethasone treated animals reverted back to normal after dexamethasone replacement and withdrawal, respectively. |
| Databáze: | OpenAIRE |
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