Transient neonatal hyperthyrotropinaemia
| Autor: | C. Y. Li, N.S. Panesar, Terence T. Lao |
|---|---|
| Rok vydání: | 1992 |
| Předmět: |
Male
endocrine system medicine.medical_specialty Cord Time Factors endocrine system diseases Birth weight Thyrotropin Internal medicine Medicine Humans Retrospective Studies Asphyxia Umbilical cord plasma business.industry Obstetrics Incidence (epidemiology) Infant Newborn Obstetrics and Gynecology Gestational age Venous Plasma medicine.disease Delivery Obstetric Congenital hypothyroidism Endocrinology Pediatrics Perinatology and Child Health Female medicine.symptom business hormones hormone substitutes and hormone antagonists Follow-Up Studies |
| Zdroj: | Early human development. 28(1) |
| ISSN: | 0378-3782 |
| Popis: | Of 48 consecutive newborns with elevated umbilical venous plasma thyrotropin (TSH) concentration, only two (4%) were subsequently proved to have congenital hypothyroidism, while the other 46 had transient elevation of TSH. Compared with matched controls, these 46 newborns were all delivered vaginally (P less than 0.0003) and had a longer second stage of labour (P less than 0.002), together with higher incidences of nuchal encirclement of the cord (P less than 0.05) as well as female babies (P less than 0.05). There was no difference in the incidence of antenatal complications, mean gestational age, birth weight, or birth asphyxia. There were no small-for-gestational age infants in the study group, while four were found in the controls. The results indicate that elevated umbilical cord plasma TSH concentration may represent a response to the stress of difficult or complicated delivery in the healthy appropriate- or large-for-gestational age newborn who does not have congenital hypothyroidism. |
| Databáze: | OpenAIRE |
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