Neuroimaging findings in 41 low-functioning children with autism spectrum disorder: a single-center experience
| Autor: | Daria Riva, Sara Bulgheroni, Chiara Vago, Alessandra Erbetta, Silvia Esposito, Luisa Chiapparini, Valeria Elisa Contarino |
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| Rok vydání: | 2013 |
| Předmět: |
Male
Pediatrics medicine.medical_specialty Adolescent Neuroimaging Single Center Autistic spectrum Intellectual disability medicine Image Processing Computer-Assisted Humans Psychiatry Child Radionuclide Imaging Retrospective Studies Chi-Square Distribution medicine.diagnostic_test Brain Magnetic resonance imaging medicine.disease Autism spectrum disorder Child Development Disorders Pervasive Endophenotype Child Preschool Pediatrics Perinatology and Child Health Autism Female Neurology (clinical) Psychology |
| Zdroj: | Journal of child neurology. 29(12) |
| ISSN: | 1708-8283 |
| Popis: | The data on the rate of brain imaging abnormalities in autistic spectrum disorders are still inconsistent. A recent study on patients with high-functioning autism found that approximately 90% of children had normal magnetic resonance imaging (MRI) scans whereas an unexpected high rate of MRI abnormalities was reported in 77 nonsyndromic autistic children with or without intellectual disability. The aim of this study was to evaluate the prevalence of neuroradiologic findings in low-functioning autistic children compared to controls matched for age. Minor brain abnormalities were found in 44% of patients and 22% of controls. Our main result is the high rate of mega cisterna magna in autistic patients. High rate of minor neuroradiologic abnormalities in low-functioning autistic patients could contribute to the research about the various endophenotypes and complete the clinical assessment of children with autistic spectrum disorder and intellectual disability. |
| Databáze: | OpenAIRE |
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