Local elasticity of the aorta in patients with type 2 diabetes mellitus
| Autor: | Barbara Mosiewicz-Madejska, Grzegorz Dzida, Jerzy Mosiewicz, Marcin Trojnar, Bogusław Makaruk, Malgorzata Dec-Gilowska |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Prospective Clinical Research Report
insulin medicine.medical_specialty Medicine (General) hypertension endocrine system diseases type 2 diabetes mellitus compliance index Blood Pressure 030209 endocrinology & metabolism 030204 cardiovascular system & hematology Biochemistry 03 medical and health sciences Vascular Stiffness 0302 clinical medicine R5-920 medicine.artery Internal medicine Ascending aorta medicine Humans In patient Elasticity (economics) Aorta business.industry Biochemistry (medical) Aortic stiffness Stiffness Type 2 Diabetes Mellitus nutritional and metabolic diseases Cell Biology General Medicine Cross-Sectional Studies medicine.anatomical_structure Diabetes Mellitus Type 2 Cardiology elasticity medicine.symptom business Artery |
| Zdroj: | Journal of International Medical Research, Vol 48 (2020) The Journal of International Medical Research |
| ISSN: | 1473-2300 |
| Popis: | Objective Arterial elasticity is important for assessing the state of an artery. This cross-sectional study aimed to non-invasively examine stiffness parameters of the ascending aorta in patients with type 2 diabetes mellitus (T2DM). Methods We studied 58 patients, including 38 with T2DM and 20 controls. The stiffness of the aorta was evaluated during transthoracic echocardiography. Aortic parameters of stiffness, such as the stiffness index, elasticity index, and compliance index, were calculated using the aortic maximal diameter, aortic minimal diameter, and blood pressure. Results Pulse pressure values were significantly higher patients with T2DM than in controls. The β index was significantly higher in patients with T2DM lasting for >7 years compared with those with T2DM lasting for Conclusions Patients with T2DM, especially when T2DM is long-term, have increased stiffness and decreased compliance of the ascending aorta. Pulse pressure, which is a cardiovascular risk factor, is also significantly increased in patients with T2DM. |
| Databáze: | OpenAIRE |
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