Marrow transplantation for acute nonlymphoblastic leukemia in first remission using fractionated or single-dose irradiation
| Autor: | Robert W. McGuffin, J.W. Smith, Clift Ra, Jean E. Sanders, Thomas Ed, Alexander Fefer, R Storb, Patricia S. Stewart, John Hersman, C. D. Buckner |
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| Rok vydání: | 1982 |
| Předmět: |
Adult
Cancer Research medicine.medical_specialty Adolescent Cyclophosphamide medicine.medical_treatment Gastroenterology Internal medicine medicine Humans Radiology Nuclear Medicine and imaging Child Bone Marrow Transplantation Leukemia Radiation business.industry Radiotherapy Dosage Immunosuppression Middle Aged Total body irradiation medicine.disease Radiation therapy Regimen Haematopoiesis medicine.anatomical_structure Oncology Child Preschool Acute Disease Bone marrow Nuclear medicine business Whole-Body Irradiation medicine.drug |
| Zdroj: | International Journal of Radiation Oncology*Biology*Physics. 8:817-821 |
| ISSN: | 0360-3016 |
| DOI: | 10.1016/0360-3016(82)90083-9 |
| Popis: | Fifty-three patients with acute nonlymphoblastic leukemia in first remission were treated with cyclophosphamide, total body irradiation and marrow transplantation. Twenty-seven patients received 1000 rad in one exposure and 12 are living in remission 6–29 months later. Twenty-six received 200 rad on each of 6 days and 18 are living in remission after 4–27 months. Kaplan-Meier analysis shows a survival advantage for the fractionated regimen (p = 0.05). |
| Databáze: | OpenAIRE |
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