The Placebo Response in Adult ADHD as Objectively Assessed by the TOVA Continuous Performance Test
| Autor: | Abraham Weizman, Ann Rotem, Jeffrey H. Newcorn, Rachel Ben-Hayun, Iris Manor, Joseph Ben-Sheetrit, Yaron Danieli, Miriam Peskin, Pavel Golubchik |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Adult
medicine.medical_specialty Composite score Audiology Correlation Test of Variables of Attention Double-Blind Method Rating scale mental disorders Developmental and Educational Psychology medicine Humans Partial correlation Retrospective Studies Placebo response Methylphenidate Reproducibility of Results Placebo Effect Test (assessment) Clinical Psychology Treatment Outcome Attention Deficit Disorder with Hyperactivity Delayed-Action Preparations Central Nervous System Stimulants Psychology medicine.drug |
| Zdroj: | Journal of Attention Disorders. 25:1311-1320 |
| ISSN: | 1557-1246 1087-0547 |
| Popis: | Objective: We compared the placebo response (PR) as measured by the Test of Variables of Attention (TOVA) and the Conners’ Adult ADHD Rating Scale (CAARS) scores. Method: A retrospective data analysis from a double-blind placebo-controlled study of metadoxine-ER in adults with ADHD. An additional database was used for comparison to TOVA response after methylphenidate challenge (TOVA-MPH-R). Results: PR was highest when calculated from the TOVA-Attention Composite Score (ACS). The PR showed significantly fewer variables improving concomitantly compared with MPH-R. The most prominent correlation between the CAARS-PR and the TOVA-PR was in the Omissions score ( p = .032), which was age-dependent ( b = .0007, p |
| Databáze: | OpenAIRE |
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