Management and prevention of varicella and measles infections in pediatric solid organ transplant candidates and recipients: An IPTA survey of current practice

Autor: Dimitri Van der Linden, Laure F Pittet, Upton Allen, Abanti Chaudhuri, Monica I. Ardura, Klara M. Posfay-Barbe, Michael Green, Marian G. Michaels, E. Goddard, Lara Danziger-Isakov, Britta Höcker
Přispěvatelé: UCL - SSS/IREC/PEDI - Pôle de Pédiatrie, UCL - (SLuc) Service de pédiatrie générale
Rok vydání: 2020
Předmět:
Male
medicine.medical_specialty
Pediatric transplantation
Population
Measles Vaccine
030232 urology & nephrology
030230 surgery
Pediatrics
Measles
Chickenpox Vaccine
03 medical and health sciences
0302 clinical medicine
Chickenpox
Surveys and Questionnaires
Health care
Practice Patterns
Physicians' / statistics & numerical data
Medicine
Humans
Practice Patterns
Physicians'
education
Child
Chickenpox Vaccine / administration & dosage
Measles / prevention & control
Transplantation
education.field_of_study
ddc:618
business.industry
fungi
Measles Vaccine / administration & dosage
food and beverages
Organ Transplantation
medicine.disease
Perinatology
Transplant Recipients
3. Good health
and Child Health
Chickenpox / prevention & control
Current practice
Family medicine
Pediatrics
Perinatology and Child Health
Female
business
Solid organ transplantation
Zdroj: Pediatric Transplantation, Vol. 24, No 8 (2020) P. e13830
Pediatric Transplantation, Vol. 24, no. 8, p. e13830 (2020)
ISSN: 1399-3046
1397-3142
Popis: BACKGROUND: Varicella and measles infections can be life-threatening after solid organ transplantation (SOT) but may be preventable with live-attenuated vaccines (LAV). METHODS: This survey conducted in January 2019 among subscribers of the International Pediatric Transplantation Association listserv aimed to explore the current strategies to prevent and manage both infections in the pediatric SOT population, including recommending LAV after SOT. RESULTS: The answers given by 95 pediatric SOT healthcare workers show that these strategies are not yet optimal and call for further education. In particular, 59% of respondents are unnecessarily waiting for a SOT candidate to be >1 year of age to start administrating LAV before SOT. Interestingly, most respondents are willing to administer LAV after SOT (57%), and a fifth (21%) are already doing so, off-label. The survey queried the precautions taken to improve safety evaluations after LAV, and identified knowledge gaps and practitioners' concerns. CONCLUSION: The results of this survey could be used as a starting point for education and promotion of the safe administration of LAV in carefully selected SOT recipients; in turn, this would increase available data that would contribute to the development of evidence-based guidelines by the transplant societies and ultimately prevent these infections after SOT.
Databáze: OpenAIRE
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje