Guidelines for the diagnosis and treatment of neuroangiostrongyliasis: updated recommendations
| Autor: | Gerald S Murphy, Jourdan K. McMillan, B C Meyer, Kenton J. Kramer, Vernon Ansdell, Olivia A. Smith, Marian E. Melish, Elizabeth U. Blalock, Louis Lteif, William L. Gosnell, Johnnie Yates |
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| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
030231 tropical medicine MEDLINE Review Article Disease Biology Albendazole Hawaii law.invention 03 medical and health sciences 0302 clinical medicine Adrenal Cortex Hormones law Diagnosis medicine Animals Humans 030212 general & internal medicine Intensive care medicine Polymerase chain reaction Strongylida Infections Anthelmintics Task force Angiostrongylus cantonensis Treatment Infectious Diseases Neuroangiostrongyliais Animal Science and Zoology Parasitology Lungworm medicine.drug |
| Zdroj: | Parasitology |
| ISSN: | 1469-8161 0031-1820 |
| DOI: | 10.1017/s0031182020001262 |
| Popis: | A subcommittee of the Hawaii Governor's Joint Task Force on Rat Lungworm Disease developed preliminary guidelines for the diagnosis and treatment of neuroangiostrongyliasis (NAS) in 2018 (Guidelines, 2018). This paper reviews the main points of those guidelines and provides updates in areas where our understanding of the disease has increased. The diagnosis of NAS is described, including confirmation of infection by real-time polymerase chain reaction (RTi-PCR) to detect parasite DNA in the central nervous system (CNS). The treatment literature is reviewed with recommendations for the use of corticosteroids and the anthelminthic drug albendazole. Long-term sequelae of NAS are discussed and recommendations for future research are proposed. |
| Databáze: | OpenAIRE |
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