Live birth resulting from a conjoined oocyte confirmed as euploid using array CGH: a case report
| Autor: | Juliette Koch, Suha Kilani, Lisa Cummins |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Adult
medicine.medical_specialty Gestational sac Oocyte Retrieval Biology 03 medical and health sciences 0302 clinical medicine Pregnancy medicine Humans 030212 general & internal medicine Zona pellucida Preimplantation Diagnosis Gynecology Comparative Genomic Hybridization 030219 obstetrics & reproductive medicine Germinal vesicle Blastocyst Transfer Infant Newborn Obstetrics and Gynecology Embryo culture medicine.disease Oocyte medicine.anatomical_structure Reproductive Medicine embryonic structures Oocytes Female Live birth Live Birth Developmental Biology |
| Zdroj: | Reproductive biomedicine online. 32(1) |
| ISSN: | 1472-6491 |
| Popis: | The significance of conjoined oocytes in the clinical IVF laboratory setting has been of question due to the extremely limited data available. The most reliable criterion for true binovularity is the inclusion of two oocytes within a common zona pellucida or their fusion in the zonal region. This is a relatively rare event and owing to the limited number of embryo transfers performed and information on their outcomes, it is highly probable that these oocytes would be discarded without attempts at fertilization and subsequent embryo culture. To our knowledge, this is the first reported pregnancy resulting from a conjoined oocyte. Our experience involved a blastocyst transfer of a genetically screened embryo, performed after removal of the germinal vesicle from the conjoined oocyte/embryo on day 3. A clinical pregnancy with a gestational sac and fetal heartbeat was achieved and a healthy baby girl was delivered via Caesarean section at 37 weeks' gestation. |
| Databáze: | OpenAIRE |
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