The Effect of Female Hormone Manipulation on Nasal Physiology
| Autor: | Anne Robinson, Carl Philpott, George E. Murty, Charlotte R. Wolstenholme, Julian Anthony Gaskin |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
Adult
Rhinometry Acoustic medicine.medical_specialty Female sex hormones medicine.medical_treatment Beta-Estradiol Fertilization in Vitro Olfaction Nose Ovarian hormone Hormone manipulation 03 medical and health sciences Follicle-stimulating hormone 0302 clinical medicine Internal medicine medicine Humans 030212 general & internal medicine 030223 otorhinolaryngology In vitro fertilisation Estradiol business.industry Rhinomanometry Smell Endocrinology Otorhinolaryngology Mucociliary Clearance Quality of Life Female Nasal physiology business |
| Zdroj: | American Journal of Rhinology. 21:675-679 |
| ISSN: | 1539-6290 1050-6586 |
| DOI: | 10.2500/ajr.2007.21.3109 |
| Popis: | Background This study was performed to establish whether the ovarian hormone beta-estradiol has any influence on nasal physiology when manipulated during in vitro fertilization treatment. Methods Women undergoing in vitro fertilization (IVF) treatment at the Assisted Conception Unit, Leicester Royal Infirmary, were recruited. Nasal peak inspiratory flow rate, acoustic rhinometry, anterior rhinomanometry, mucociliary clearance, olfactory thresholds, quality of life, and serum 17-beta-estradiol levels were measured at each visit. Subjects were studied at the beginning of their IVF treatment and then at one or two additional occasions while they received synthetic follicule-stimulating hormone with a final set of results taken at the end of their treatment. Results Results were analyzed using paired t-tests. There was no statistical difference between any of the data sets for any of the variables during the process of IVF treatment. Conclusion Increasing levels of beta-estradiol that occur in IVF treatment cause no significant effect on nasal physiology in contrast to the effects seen during pregnancy. |
| Databáze: | OpenAIRE |
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