The role of autonomic and baroreceptor reflex control in blood pressure dipping and nondipping in rats

Autor: Yi Ping Wang, Kai Ho Mak, Cheryl C.H. Yang, Guo She Lee, Chun Yu Chen, Terry B.J. Kuo, Yi Yun Lan
Rok vydání: 2014
Předmět:
Zdroj: Journal of Hypertension. 32:806-816
ISSN: 0263-6352
DOI: 10.1097/hjh.0000000000000099
Popis: AIMS This study hypothesized that the sleep-wake cycle is the major determinant factor affecting blood pressure (BP) dipping in rats and that the sympathovagal imbalance during quiet sleep is associated with the degree of BP fall. METHODS Polysomnographic recording was performed by telemetry on freely moving Wistar-Kyoto rats over 24 h. Active waking and quiet sleep stages were scored using electroencephalogram and electromyogram. BP dipping was assessed as the percentage decline in SBP from dark active waking to light quiet sleep. About 38% of the rats were classified as dippers (>10% dip) and 62% as nondippers (
Databáze: OpenAIRE