Changes in Hematologic and Coagulation Profiles in Rabbits with Right-ventricle Pacing
Autor: | Katerina Machackova, Peter Kruzliak, Pavel Suchy, Delian Delev, Jana Hlozkova, I. Uhrikova, Peter Scheer, Rachele Ciccocioppo, Marta Kasajova, Milan Sepši |
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Jazyk: | angličtina |
Rok vydání: | 2016 |
Předmět: |
0301 basic medicine
Male Pacemaker Artificial lcsh:Medicine 030204 cardiovascular system & hematology Hematocrit Leukocyte Count Hemoglobins 0302 clinical medicine Coagulation testing Medicine skin and connective tissue diseases coagulation profile medicine.diagnostic_test Cardiac Pacing Artificial General Medicine Flow Cytometry Thrombelastography Pacemaker Anesthesia Artificial Partial Thromboplastin Time Differential Leukocyte Count Rabbits Partial thromboplastin time Heart Ventricles right-ventricle pacing Fibrin Fibrinogen Degradation Products 03 medical and health sciences Animals Blood Cell Count Blood Coagulation Erythrocyte Count Fibrinogen Platelet Count Prothrombin Time Hemostasis D-dimer Prothrombin time business.industry lcsh:R thromboelastography Thromboelastography 030104 developmental biology Cardiac Pacing sense organs business |
Zdroj: | Folia Medica, Vol 58, Iss 2, Pp 89-94 (2016) |
Popis: | Objectives: The aim of this study was to evaluate changes in hematology and coagulation in rabbits with right-ventricle pacing without medication. Animals and methods: Blood was collected from ten non-anesthetized male rabbits from the jugular vein before and one month after pacemaker placement. Total erythrocyte, leukocyte and platelet count, hemoglobin, hematocrit and differential leukocyte count were done on automatic veterinary flow cytometry hematologic analyzer. Prothrombin time, activated partial thromboplastin time, fibrinogen level, D-dimers and kaolin-activated thromboelastography was measured from citrated blood. Results: We found an increase in red blood cell mass and decrease in platelet count, while coagulation tests did not diff er between samplings. Conclusion: Right-ventricle pacing seems to have no influence on hemostasis in rabbits. |
Databáze: | OpenAIRE |
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