Multimodal psychosocial intervention for family caregivers of patients undergoing hematopoietic stem cell transplantation: A randomized clinical trial
| Autor: | Areej El-Jawahri, Alyssa L. Fenech, Annemarie D. Jagielo, Jennifer D'Alotto, Jamie M. Jacobs, Showly Nicholson, Lara Traeger, Yi Bin Chen, Joseph A. Greer, Lauren Waldman, Zachariah DeFilipp, Ashley M. Nelson, Thomas R. Spitzer, Jennifer S. Temel, Nora Horick |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
Male Cancer Research Coping (psychology) medicine.medical_specialty Social Workers Anxiety Hospital Anxiety and Depression Scale Article law.invention Young Adult 03 medical and health sciences 0302 clinical medicine Randomized controlled trial law Neoplasms Adaptation Psychological Clinical endpoint Humans Medicine 030212 general & internal medicine Aged Aged 80 and over Depression Family caregivers business.industry Hematopoietic Stem Cell Transplantation Middle Aged surgical procedures operative Mood Caregivers Oncology 030220 oncology & carcinogenesis Quality of Life Physical therapy Female medicine.symptom business Psychosocial |
| Zdroj: | Cancer |
| ISSN: | 1097-0142 0008-543X |
| Popis: | BACKGROUND Caregivers of patients undergoing hematopoietic stem cell transplantation (HCT) experience an immense caregiving burden before, during, and after HCT. METHODS We conducted an unblinded, randomized trial of a psychosocial intervention (BMT-CARE) for caregivers of patients undergoing autologous and allogeneic HCT at Massachusetts General Hospital. Caregivers were randomly assigned to BMT-CARE or usual care. BMT-CARE was tailored to the HCT trajectory and integrated treatment-related education and self-care with cognitive-behavioral skills to promote coping. Caregivers assigned to BMT-CARE met with a trained interventionist (a psychologist or a social worker) in person, via telephone, or via videoconferencing for 6 sessions starting before HCT and continuing up to day +60 after HCT. The primary endpoint was feasibility, which was defined as at least 60% of eligible caregivers enrolling and completing 50% or more of the intervention sessions. We assesed caregiver quality of life (QOL; Caregiver Oncology Quality of Life Questionnaire), caregiving burden (Caregiver Reaction Assessment), psychological distress (Hospital Anxiety and Depression Scale), self-efficacy (Cancer Self-Efficacy Scale-Transplant), and coping (Measures of Current Status) at baseline and 30 and 60 days after HCT. We used mixed linear effect models to assess the effect of BMT-CARE on outcomes longitudinally. RESULTS We enrolled 72.5% of eligible caregivers (100 of 138), and 80% attended 50% or more of the intervention sessions. Caregivers randomized to BMT-CARE reported improved QOL (B = 6.11; 95% CI, 3.50-8.71; P |
| Databáze: | OpenAIRE |
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