Hypochlorous acid antiseptic washout improves patient comfort after intravitreal injection: A patient reported outcomes study

Autor: Kimberly J. Chin, Paul T. Finger, Gaurav Garg, Ankit Singh Tomar, Anthony Fam
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Indian Journal of Ophthalmology, Vol 68, Iss 11, Pp 2439-2444 (2020)
Indian Journal of Ophthalmology
ISSN: 1998-3689
0301-4738
Popis: Purpose: Current ocular antiseptic practice for intravitreal injection (IVI) employs 5% povidone–iodine (Betadine®) drops which frequently cause ocular discomfort and prolonged irritation. In an effort to improve comfort while maintaining efficacy, we studied a hypochlorous acid (HOCL 0.01%) spray washout prior to injection. Methods: Patients had received a minimum of 3 IVIs prepared with Betadine® antisepsis prior to entry in this study. Their subsequent IVIs were prepared with Betadine® followed by HOCL 0.01% washout. Facets of comfort were measured by a Likert-scaled questionnaire to compare their experiences after IVI. Results: Thirty-seven participants were enrolled. Addition of HOCL 0.01% spray after Betadine® reduced the duration of discomfort (P = 0.001) and need for artificial tears postinjection (P = 0.003). It improved their reported quality of life (P = 0.04) and sleep (P = 0.01). There were neither HOCL-related side effects nor endophthalmitis during this study. Conclusion: Topical HOCL 0.01% spray after topical Betadine® antisepsis significantly improved patient comfort following IVIs.
Databáze: OpenAIRE
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