Antibody responses after repeated influenza A virus immunizations among schoolchildren in Japan
| Autor: | Nobuhisa Yamane, Takato Odagiri, M. Hiratsuka, Nakao Ishida, Jiro Arikawa |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 1981 |
| Předmět: |
Hemagglutination
Adolescent viruses Immunology education Hemagglutinins Viral Neuraminidase Cross Reactions medicine.disease_cause Antibodies Viral Virus Viral Proteins Antigen Japan Influenza Human Influenza A virus medicine Humans biology Vaccination Public Health Environmental and Occupational Health virus diseases Virology Nucleoprotein Nucleoproteins Immunization biology.protein Antibody Research Article |
| Popis: | SummaryAntibody responses to influenza virus immunizations were examined among junior high school students. The students received two doses of a commercial split-product vaccine containing influenza A H1N1 during a 2-year period following the first appearance of H1N1 virus in the winter of 1977–78. In haemagglutination-inhibition (HI) tests, the students who had been infected with H1N1 virus in 1977–78 showed a better response and wider cross-reactivity to the drift strain than the students who had not experienced earlier H1N1 influenza infection. Neuraminidase-inhibition (NAI) antibody titres after immunization depended upon a history of natural infection with H1N1 virus, since students not previously infected showed no significant NAI antibody rise after immunization. |
| Databáze: | OpenAIRE |
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