Hemoglobin Changes at the Initiation of High-Flux Hemodialysis
| Autor: | T. Natse, F. Christidou, L. Gionanlis, A. Karagianni, G Bamichas, K Sombolos, C. Fytili |
|---|---|
| Rok vydání: | 2006 |
| Předmět: |
Adult
Male medicine.medical_specialty medicine.medical_treatment Bicarbonate Urology Ultrafiltration Blood volume Hematocrit Hemoglobins chemistry.chemical_compound Renal Dialysis Humans Medicine Aged Acid-Base Equilibrium Aged 80 and over Blood Volume medicine.diagnostic_test business.industry General Medicine Blood flow Middle Aged Blood proteins Surgery chemistry Nephrology Arterial line Female Hemoglobin Hemodialysis business |
| Zdroj: | Nephron Clinical Practice. 105:c29-c34 |
| ISSN: | 1660-2110 |
| Popis: | Background: The aim of the present study was to assess hemoglobin changes occurring at the beginning of high-flux hemodialysis (HD). Methods: In a group of 20 chronic HD patients (group A), total hemoglobin (tHb), hematocrit (Hct) and total serum proteins (TP) were measured in blood samples drawn from an arterial fistula needle before the initiation of high-flux HD, and from an arterial line 5 min after HD with the dialysate in the bypass mode. 31 chronic stable HD patients (group B) served as controls. In group B patients, tHb was measured in blood samples drawn from an arterial fistula needle before the initiation of high-flux HD, and from arterial and venous lines simultaneously 5 min later. Blood flow rates in groups A and B were set from the beginning of the study to 300 ml/min, while the bicarbonate dialysate flow rate and ultrafiltration rate in group B patients was set to 700 ml/min and zero, respectively. The same high-flux dialyzer was used for all patients (FLX-18, membrane PEPA 1.8 m2). Results: A comparison of baseline (pre-dialysis) values with those derived from an analysis of the arterial line in groups A and B at 5 min revealed that tHb decreased by 0.6 ± 0.2 g/dl (5.2 ± 1.7%, p < 0.001) and 0.7 ± 0.7 g/dl (5.4 ± 6.2%, p < 0.001), respectively. At the same time, Hct and TP in group A decreased by 1.32 ± 0.7% (3.8 ± 2.0%, p Conclusion: A 5% decrease in tHb was observed 5 min after the initiation of high-flux HD with a zero ultrafiltration rate, and was due to an increase in BV. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|