Management of Bone Metastases in Patients with Castration-Resistant Prostate Cancer
| Autor: | Zoltan Bajory, Ahmed El Ghoneimy, Gero Kramer, Frederico Goncalves, Gabriel Kacso, Wahid Tantawy, Krzystof Lesniewski-Kmak, Mounira Bouzid, Piotr Milecki, Richard Cathomas, Silke Gillessen, Dalibor Pacik |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Male
Oncology medicine.medical_specialty Urology medicine.medical_treatment Bone Neoplasms Castration resistant Antibodies Monoclonal Humanized Medical Oncology Zoledronic Acid Bone and Bones Prostate cancer Quality of life Spinal cord compression Internal medicine Humans Medicine In patient 03.02. Klinikai orvostan Neoplasm Metastasis Bone Density Conservation Agents Diphosphonates business.industry Imidazoles medicine.disease Radiation therapy Prostatic Neoplasms Castration-Resistant Treatment Outcome Zoledronic acid Denosumab Quality of Life Interdisciplinary Communication business Spinal Cord Compression medicine.drug |
| Zdroj: | Urologia Internationalis. 92:377-386 |
| ISSN: | 1423-0399 0042-1138 |
| Popis: | Bone metastases are a very common problem in prostate cancer. They are associated with considerable morbidity, adversely affect quality of life and frequently lead to advanced bone events (so-called skeletal-related events, SREs); SREs include fractures, spinal cord compression and the requirement for bone surgery or bone radiation. The aim of this paper was to evaluate currently available treatment options in the prevention and management of SREs and bone metastases in men with castration-resistant prostate cancer and to outline the importance of interdisciplinary management strategies. It also discusses the diagnostic workup of osseous metastases and practical considerations for the utilization of bone-targeted therapies in accordance with current guidelines to provide a consensus for special and/or difficult clinical situations. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|