Cardiovascular risk factor analysis in patients with a recent clinical fracture at the fracture liaison service
| Autor: | Caroline E. Wyers, Piet Geusens, Joop P. W. van den Bergh, Heinrich M. J. Janzing, Lisanne Vranken, J. Wim Morrenhof, Robert Y. van der Velde |
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| Přispěvatelé: | Interne Geneeskunde, Health Services Research, RS: CAPHRI School for Public Health and Primary Care, RS: CAPHRI - Redesigning Health Care, RS: CAPHRI - Diagnosis and treatment of frequently occuring diseases in general practice, RS: CAPHRI - Effectiveness of Diagnosis and Intervention in patients with Rheumatic Diseases |
| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
Male
medicine.medical_specialty Article Subject lcsh:Medicine Comorbidity General Biochemistry Genetics and Molecular Biology Age Distribution Strontium ranelate Risk Factors Diabetes mellitus Internal medicine medicine Humans Medical history Raloxifene cardiovascular diseases Sex Distribution Risk factor Aged Netherlands Aged 80 and over Bone mineral General Immunology and Microbiology business.industry Incidence Incidence (epidemiology) lcsh:R General Medicine Middle Aged medicine.disease Surgery Diabetes Mellitus Type 2 Traumatology Cardiovascular Diseases Biotechnology & Applied Microbiology Medicine Research & Experimental Female business Osteoporotic Fractures Research Article medicine.drug |
| Zdroj: | BioMed Research International BioMed Research International, Vol 2014 (2014) BioMed Research International, 2014:710945. Hindawi Publishing Corporation |
| ISSN: | 2314-6141 2314-6133 |
| Popis: | Patients with a low bone mineral density have an increased risk of cardiovascular diseases (CVD) and venous thromboembolic events (VTE). The aim of our retrospective chart review was to investigate the prevalence of CVD, VTE, hypertension (HT), and diabetes mellitus type 2 (DM2) in patients with a recent clinical fracture visiting the Fracture Liaison Service (FLS). Out of 3057 patients aged 50–90 years, 1359 consecutive patients, who agreed and were able to visit the FLS for fracture risk evaluation, were included (71.7% women; mean age 65.2 yrs). Based on medical history, 29.9% had a history of CVD (13.7%), VTE (1.7%), HT (14.9%), and DM2 (7.1%) or a combination. Their prevalence increased with age (21% in patients aged 50–59 years to 48% in patients aged >80 years) and was higher in men than in women (36% versus 27%), but independent of bone mineral density and fracture type. Careful evaluation of medical history with respect to these risk factors should be performed in patients with a recent clinical fracture before starting treatment with medications that increase the risk of VTE or cardiovascular events, such as raloxifene, strontium ranelate, or NSAIDs. |
| Databáze: | OpenAIRE |
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