Dose–Response Relationship of Outdoor Exposure and Myopia Indicators: A Systematic Review and Meta-Analysis of Various Research Methods
| Autor: | Ciao Lin Ho, Wei-Fong Wu, Yiing Mei Liou |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Male
Refractive error Asia Time Factors Adolescent genetic structures Health Toxicology and Mutagenesis near-sightedness lcsh:Medicine Spherical equivalent axial length Article preschool 03 medical and health sciences 0302 clinical medicine Myopia Odds Ratio Prevalence Humans Medicine 030212 general & internal medicine Child business.industry Incidence Incidence (epidemiology) lcsh:R Public Health Environmental and Occupational Health spherical equivalent refractive error (SER) Odds ratio Protective Factors medicine.disease Confidence interval eye diseases Dose–response relationship Cross-Sectional Studies Child Preschool Meta-analysis Cohort school age Sunlight 030221 ophthalmology & optometry Female business Demography |
| Zdroj: | International Journal of Environmental Research and Public Health Volume 16 Issue 14 International Journal of Environmental Research and Public Health, Vol 16, Iss 14, p 2595 (2019) |
| ISSN: | 1660-4601 |
| DOI: | 10.3390/ijerph16142595 |
| Popis: | Myopia in children has dramatically increased worldwide. A systematic review and meta-analysis were conducted to evaluate the effects of outdoor light exposure on myopia. According to research data from 13 studies of 15,081 children aged 4&ndash 14 at baseline, outdoor light exposure significantly reduced myopia incidence/prevalence (odds ratio [OR] = 0.85, 95% confidence interval [CI]: 0.80&ndash 0.91, p < 0.00001 I2 = 90%), spherical equivalent refractive error (SER) by 0.15 D/year (0.09&ndash 0.27, p < 0.0001), and axial elongation by 0.08 mm/year (&minus 0.14 to &minus 0.02, p = 0.02). The benefits of outdoor light exposure intervention, according to pooled overall results, included decreases in three myopia indicators: 50% in myopia incidence, 32.9% in SER, and 24.9% in axial elongation for individuals in Asia. Daily outdoor light exposure of more than 120 min was the most effective intervention, and weekly intervention time exhibited a dose&ndash response relationship with all three indicators. Subgroup comparisons revealed that interventional studies report greater benefits from outdoor light exposure compared with cohort and cross-sectional studies, and individuals with myopia in intervention studies experienced slightly greater benefits than individuals without, in terms of SER and axial elongation. Therefore, this study suggests 120 min/day of outdoor light exposure at school. |
| Databáze: | OpenAIRE |
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