Lower rates of protein degradation in developing rat brain
| Autor: | J L Dahl, V J Weibel |
|---|---|
| Rok vydání: | 1979 |
| Předmět: |
History
medicine.medical_specialty biology Adrenal gland medicine.medical_treatment Intraperitoneal injection Brain Proteins Protein degradation Rat brain biology.organism_classification Rats Computer Science Applications Education Protein content Bicarbonates medicine.anatomical_structure Endocrinology Biochemistry Internal medicine medicine Animals Bacteria Research Article |
| Zdroj: | Biochemical Journal. 180:423-426 |
| ISSN: | 0306-3283 |
| DOI: | 10.1042/bj1800423 |
| Popis: | Protein-degradation rates in developing rat brain were estimated from the decay in total radioactivity in proteins labelled by a single intraperitoneal injection of NaH14CO3 to 5-day-old animals. In contrast with previous reports, our results indicate that degradation rates are lower in developing than in adult brain and suggest that in brain, as has been observed in liver, adrenal gland, muscle, cultured mammalian cells and bacteria, reduced rates of protein degradation contribute to the increase in protein content under conditions of rapid growth. |
| Databáze: | OpenAIRE |
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