Neutrophil function in the healing wound: adding insult to injury?
| Autor: | Luisa A. DiPietro, Anna M. Szpaderska, Julia V. Dovi |
|---|---|
| Rok vydání: | 2004 |
| Předmět: |
Inflammation
Wound Healing Innate immune system integumentary system Neutrophils Normal wound healing business.industry Macrophages Epithelial Cells Hematology Granulocyte medicine.anatomical_structure Immune System Immunology medicine Animals Humans Macrophage Wound closure medicine.symptom Wound healing business Function (biology) Cell Proliferation |
| Zdroj: | Thrombosis and Haemostasis. 92:275-280 |
| ISSN: | 2567-689X 0340-6245 |
| DOI: | 10.1160/th03-11-0720 |
| Popis: | SummaryCells of the innate immune system, including neutrophils and macrophages, are a highly visible component of normal wound healing in adult mammals. The role of inflammatory cells in the healing wound has been widely investigated, and evidence for both positive and negative influences exists. Several recent investigations support the emerging paradigm that robust inflammation is detrimental to wound closure. This developing information suggests that the functional role of inflammatory cells in wound healing must be reevaluated. |
| Databáze: | OpenAIRE |
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