Transcatheter Aortic Valve Replacement in Rheumatic Aortic Stenosis: A Comprehensive Review
Autor: | Uzoma N. Ibebuogu, Tamunoinemi Bob-Manuel, Connor Gillies, Ivana Okor, Harith Baldawi, Kiran Garikapati |
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Rok vydání: | 2021 |
Předmět: |
Aortic valve
medicine.medical_specialty Heart disease Transcatheter aortic Rheumatic aortic stenosis medicine.medical_treatment 030204 cardiovascular system & hematology Severity of Illness Index Transcatheter Aortic Valve Replacement 03 medical and health sciences 0302 clinical medicine Aortic valve replacement Valve replacement Risk Factors Internal medicine medicine Humans 030212 general & internal medicine Heart Valve Prosthesis Implantation business.industry Calcinosis General Medicine Aortic Valve Stenosis medicine.disease Review article Stenosis medicine.anatomical_structure Treatment Outcome Aortic Valve cardiovascular system Cardiology Cardiology and Cardiovascular Medicine business |
Zdroj: | Current problems in cardiology. 46(12) |
ISSN: | 1535-6280 |
Popis: | Rheumatic heart disease (RHD) mainly affects people in developing, low-income countries. However, due to globalization and migration, developed countries are now seeing more cases of RHD. In RHD patients who develop severe symptomatic aortic stenosis, surgical aortic valve replacement remains the treatment of choice. In the past decade, there has been an extension of transcatheter aortic valve replacement (TAVR) to intermediate-risk and lower-risk patients with aortic stenosis. This review suggests the possible utility of TAVR for the treatment of rheumatic aortic stenosis. Rheumatic aortic stenosis has been excluded from major TAVR studies due to the predominantly noncalcific pathology of the rheumatic aortic valve. However, there have been case reports and case series showing successful implantation of the valve even in patients with and without significant leaflet calcification. In this review article, we summarize the latest evidence of severe rheumatic aortic stenosis treated with TAVR and discuss the procedure's impact on patient care, safety, and efficacy. |
Databáze: | OpenAIRE |
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