Tuning the inflammatory response to silver nanoparticles via quercetin in Caco-2 (co-)cultures as model of the human intestinal mucosa

Autor: Laurie Laloux, Madeleine Polet, Alina Martirosyan, Yves-Jacques Schneider, Konstantinos Grintzalis
Rok vydání: 2016
Předmět:
0301 basic medicine
Antioxidant
medicine.medical_treatment
Flavonoid
Anti-Inflammatory Agents
Metal Nanoparticles
02 engineering and technology
Toxicology
medicine.disease_cause
Silver nanoparticle
Oxidative and nitrosative stress
Lipid peroxidation
chemistry.chemical_compound
Gastrointestinal tract
Intestinal mucosa
heterocyclic compounds
Intestinal Mucosa
OXIDATIVE STRESS
chemistry.chemical_classification
EXPERIMENTAL COLITIS
Chemistry
digestive
oral
and skin physiology
Silver Compounds
General Medicine
PHENOLIC-COMPOUNDS
PEROXYNITRITE
021001 nanoscience & nanotechnology
Reactive Nitrogen Species
Biochemistry
Quercetin
Silver nanoparticles
0210 nano-technology
EXPRESSION
EPITHELIAL MONOLAYERS
Cell Survival
Risk Assessment
03 medical and health sciences
IN-VITRO MODEL
medicine
Humans
BOWEL-DISEASE
Viability assay
Inflammation
NITRIC-OXIDE
Dose-Response Relationship
Drug
Inflammatory response
Coculture Techniques
Oxidative Stress
030104 developmental biology
Cytoprotection
CELLS
Lipid Peroxidation
Caco-2 Cells
Reactive Oxygen Species
Oxidative stress
Zdroj: Martirosyan, A, Grintzalis, K, Polet, M, Laloux, L & Schneider, Y-J 2016, ' Tuning the inflammatory response to silver nanoparticles via quercetin in Caco-2 (co-)cultures as model of the human intestinal mucosa ', Toxicology Letters, vol. 253, pp. 36-45 . https://doi.org/10.1016/j.toxlet.2016.04.018
ISSN: 0378-4274
DOI: 10.1016/j.toxlet.2016.04.018
Popis: Interaction of nanoparticles with food matrix components may cause unpredictable health complications. Using an improved Caco-2 cell-based in vitro (co-)culture model the potential of quercetin as one of the major food flavonoids to alter the effect of silver nanoparticles (Ag-NPs)
Databáze: OpenAIRE
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