Amyloidoma in the gasserian ganglion: case report
Autor: | Eiichi Tani, Keizou Kaba, Masayuki Yokota, Yoshinobu Hoshii, Tsuyoshi Matsumoto, Masahiro Fukami |
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Rok vydání: | 2000 |
Předmět: |
Adult
Pathology medicine.medical_specialty Amyloid Amyloid Neuropathies Lesion Trigeminal ganglion Eosinophilic medicine Cranial nerve disease Humans Trigeminal nerve Amyloidoma business.industry Amyloidosis Anatomy medicine.disease Magnetic Resonance Imaging Ganglion medicine.anatomical_structure Trigeminal Ganglion Trigeminal Nerve Diseases Surgery Female Neurology (clinical) medicine.symptom business |
Zdroj: | Surgical neurology. 52(6) |
ISSN: | 0090-3019 |
Popis: | BACKGROUND Amyloidoma in the central nervous system is extremely rare. We describe a rare case of amyloidoma in the gasserian ganglion manifesting as trigeminal neuropathy. METHODS A 41-year-old woman was admitted to our hospital with progressive numbness and hypalgesia in the distribution of the second and third divisions of the left trigeminal nerve. There was no evidence of chronic inflammatory disorder or immunological abnormalities. Magnetic resonance images showed a mass in the left Meckel’s cave that was brightly enhanced with gadolinium. RESULTS A reddish, firm mass was successfully removed via a left temporal craniotomy. Histologically, the tumor was composed of larger acellular deposits of eosinophilic material. The acellular deposits were positive for potassium permanganate-resistant Congo red staining, showing apple-green birefringence under polarized light and expression of immunoglobulin λ light chain-derived proteins (Aλ) immunohistochemically. CONCLUSION The present case revealed an Aλ amyloidoma in the left gasserian ganglion. Although the incidence is rare, amyloidoma should be suspected in patients who complain of progressive trigeminal neuropathies and show an enhanced lesion in the gasserian ganglion on MR images. |
Databáze: | OpenAIRE |
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