A functionalized biological heart valve by double bond crosslinking with enhanced biocompatibility and antithrombogenicity

Autor:	Cheng Zheng, Dajun Kuang, Kailei Ding, Xueyu Huang, Hongsong Fan, Li Yang, Yunbing Wang, Xingdong Zhang
Rok vydání:	2022
Předmět:	Biomedical Engineering General Materials Science General Chemistry General Medicine
Zdroj:	Journal of Materials Chemistry B. 10:10001-10017
ISSN:	2050-7518 2050-750X
Popis:	With the advancement of minimally invasive interventional therapy, biological heart valves (BHVs) have been extensively used in clinics. However, BHVs are generally prone to degeneration within 10-15 years after implantation due to defects including cytotoxicity, immune response, calcification and thrombosis, which are closely related to glutaraldehyde-crosslinking. In this work, we prepared a functionalized BHV through the
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e21752db89c7d156b7a29fdc2b499e2 https://doi.org/10.1039/d2tb02218d Zobrazit plný text záznamu